Vitiligo

Vitiligo is a chronic skin condition characterized by the loss of skin pigment, which results in irregular white patches on the skin. The condition occurs when melanocytes, the cells responsible for producing the pigment melanin, are destroyed or stop functioning. This leads to areas of skin where melanin is no longer produced, creating lighter patches.
Vitiligo occurs in over 1% of the population throughout the world.
Loss of skin colour can affect any part of the body, including the mouth, hair and eyes.

Vitiligo

 

Causes

  • The exact cause of vitiligo is not fully understood, but it is thought to involve a combination of genetic, environmental, and autoimmune factors.
  • The immune system mistakenly attacks and destroys melanocytes. This can be triggered by genetic factors or other unknown triggers, such as stress, skin trauma, or infection.
  • Vitiligo is commonly associated with other autoimmune conditions, such as thyroid disorders (e.g., hypothyroidism or hyperthyroidism), diabetes, or pernicious anemia.

Symptoms:

  • Depigmented patches: The most obvious symptom is the appearance of white or lighter patches of skin. These patches can occur anywhere on the body, though they are most commonly seen on the hands, feet, face, or areas that are often exposed to the sun.
  • Premature graying of hair: Vitiligo can also affect hair color, leading to white or gray hair in areas with depigmentation.

Diagnosis:

  • Clinical examination: A healthcare provider will usually diagnose vitiligo based on its characteristic appearance and medical history.
  • Wood’s lamp examination: This is a special ultraviolet light used to illuminate the skin and highlight the depigmented patches, making them more visible.
  • Skin biopsy: In some cases, a small sample of skin may be taken for analysis to rule out other skin conditions or confirm the diagnosis.
  • Blood tests: To check for autoimmune conditions or underlying diseases that may be related to vitiligo.

Treatment

The current management of vitiligo remains challenging; however, different strategies are proposed to patients with a good efficacy. First, it is important to identify patients in the active phase of the disease because treatment should start as soon as possible to halt its progression.

The goal is usually to restore pigment, prevent further depigmentation, and improve cosmetic appearance.

Common treatments for vitiligo include:

  • Medications
  • Light therapy- Narrowband UVB therapy is one of the most common treatments for vitiligo. It involves exposing the skin to ultraviolet light under controlled conditions. This therapy can stimulate melanocytes to produce melanin.
  • Depigmentation therapy.- Depigmentation therapy removes the color of your natural skin tone to match areas of your skin affected with vitiligo.
  • Cosmetic camouflage - Some people with vitiligo choose to use makeup or body cover products to mask the depigmented patches. These are not medical treatments but can help to restore a more even appearance
  • Surgery - Surgical treatments are useful for localized and stable vitiligo, as well as for segmental vitiligo.

Is Vitiligo curable ?

Currently, vitiligo is not curable, but it is treatable. The goal of treatment is to manage the condition by slowing its progression, stimulating repigmentation of the skin, and improving cosmetic appearance.

Is vitiligo painful?

No, vitiligo isn’t painful. However, you can get painful sunburns on lighter patches of skin affected by vitiligo. Therefore sun protection is must

Sunscreen: Since vitiligo patches have no pigment and are vulnerable to sunburn, using high-SPF sunscreen on affected areas is important to protect the skin from UV damage.

Coping with Vitiligo:

Vitiligo can have a significant psychological impact, as people with the condition may feel self-conscious about their appearance. Support from mental health professionals, support groups, or counseling can be beneficial for managing the emotional aspects of living with vitiligo. Additionally:

  • Acceptance and self-confidence: Learning to embrace one’s appearance and seeking acceptance from others can help improve quality of life.
  • Education: Understanding that vitiligo is a non-contagious, genetic condition may help reduce stigma and improve social interactions.

Prognosis:

  • Variable progression: The progression of vitiligo is unpredictable. In some people, the depigmentation stops after a few patches appear, while in others, it can spread across the body over time.
  • Remission: Some people experience spontaneous repigmentation or periods of remission, where the patches begin to regain color, though this is not always permanent.